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Treatment of Henoch Schonlein Purpura Nephropathy

2017-11-09 17:24

Purpura nephritis, renal failure or uremia are purpura persistent renal damage nephritis symptoms, purpura nephritis failure or improper treatment, resulting in deterioration of renal function. Purpura nephritis renal failure is a summary of the disease after renal decompensation, uremic purpura uremia is actually the final stage of purpura nephritis end stage renal failure. The two are from the initial Henoch Schonlein purpura disease to the kidney damage.

Treatment of Henoch Schonlein Purpura Nephropathy

The essence of allergic purpura is a kind of allergic inflammation, can cause multiple parts of the skin, joints, internal organs disease, most patients with renal involvement, namely allergic purpura nephritis, renal involvement is one of the common causes of pediatric systemic diseases. The prognosis of Henoch Schonlein purpura mainly depends on whether the kidney is involved and its degree, so it is necessary to strengthen the understanding of Henoch Schonlein purpura, in order to ensure that children and their families adhere to long-term follow-up, regular treatment.

Henoch Schonlein purpura nephritis is a secondary glomerular disease, also known as allergic purpura nephritis. The age of onset of Henoch Schonlein purpura nephritis were mostly around the age of 12, it is not rare in adults, more men than women, occurs in the autumn summer between generally associated with infection, food, drug or pollen related allergy caused by capillary. Most of the renal involvement occurs within one month after the onset of the disease. Microalbuminuria and microscopic hematuria are present in the clinic, and a small number of proteinuria is nephrotic syndrome. Most of the patients for a period of time in hematuria and proteinuria after symptoms gradually improved until healed, a part of patients with persistent symptoms, progressive deterioration of renal function, leading to renal failure in critically ill patients can occur in the short term, oliguria, hypertension, renal dysfunction, urinary sepsis development.

Allergic purpura at present there is no specific treatment, should as far as possible to find out the possible sources of allergy, and gastrointestinal symptoms can be removed, symptomatic spasm treatment, adrenal cortical hormone to alleviate joint and gastrointestinal symptoms have some help, but short-term application. Secondly, for purpura nephritis, purpura nephritis and renal failure or purpura nephritis uremia, clinicians should according to the symptoms and renal pathology, inpidualized treatment, mild oral medicine can, or need corticosteroid and cyclophosphamide immunosuppressant treatment. Cyclophosphamide and other cytotoxic drugs, the curative effect is not sure, and side effects are larger. Traditional Chinese medicine (TCM) has advantages and special advantages in the treatment of this disease, and the combination of TCM and Western medicine can significantly improve the curative effect.


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