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How to treat diabetic nephrosis?

2017-07-21 16:43

There is no specific treatment for diabetic nephropathy. The principle of treatment is to strictly control blood sugar, to keep blood sugar close to normal level, to prevent and delay the occurrence of diabetic nephropathy, to delay the decline of renal function, to take dialysis and transplant kidneys.

1, the strict control of blood glucose; before the emergence of clinical diabetic nephropathy, which is in the early stage of diabetes, take insulin pump or subcutaneous injection of insulin to maintain diabetes and keep blood glucose basically in normal; these can delay or even prevent the occurrence and development of diabetic nephropathy, reduce the increased glomerular filtration rate and improve the urinary albumin, also beneficial to other complications. When diabetic nephropathy occurs, hypoglycemic agents should generally be switched to insulin.

2, limiting protein intake, and properly reducing the amount of protein in the diet (0, 8//kg, d) can reduce glomerular pressure, reduce high filtration and reduce urinary protein. Conversely, high protein diets can exacerbate kidney damage. People who already suffer from kidney failure should limit protein intake and eat protein containing rich essential amino acids.

3, control hypertension, hypertension will promote the development of renal failure, effective antihypertensive treatment can slow down the decreasing rate of glomerular filtration rate, and reduce the excretion of urinary albumin. Angiotensin converting enzyme inhibitors or angiotensin II receptor antagonists can be used as priority choice drugs and often need to be combined with other antihypertensive agents, such as calcium antagonists, diuretics, beta blockers, etc.. When the blood pressure of patients with diabetes is more than 130/80mmHg, they should be treated with antihypertensive drugs and the pressure should be controlled under 130/80mmHg; for patients whose urinary protein is more than 1g/24 hours, their blood pressure should be controlled in 125/75mmHg. Antihypertensive treatment is also beneficial for diabetic retinopathy. But elder patients with renal insufficiency or high serum creatinine patients should be cautious with angiotensin converting enzyme inhibitors or angiotensin II receptor antagonists(such as Lotensin, losartan, irbesartan, Diovan, etc.) and especially the occurring of hyperkalemia.

4 dialysis treatment and renal transplantation; once renal failure occurs, dialysis treatment and renal transplantation are effective methods.

How to treat diabetic nephrosis

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