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Early detection and early treatment for diabetic nephropathy

2017-07-21 16:42

Diabetic nephropathy can be pided into five stages. The first stage is glomerular hyperfiltration; high filtration seems showing a strong kidney function, but in fact the kidneys work overload in high filtration; it will quickly enter the second phase and it is not good things. Good glycemic controlling and weight controlling relieve high filtration. It still can have high filtration in the second stage; high filtration in some patients disappeared; exercise can induce microalbuminuria, but it is reversible. Albuminuria begins at the third stage and is initially microalbuminuria. During this period, if getting good control of blood sugar, blood pressure, blood lipids, diet, weight, microalbuminuria can disappear in some patients. With the development of diabetic nephropathy, kidney disease is more and more serious, urinary albumin increased gradually, eventually diabetic nephropathy developed into the fourth stage; albuminuria appeared in clinical and conventional method can detect the urine albumin in this stage. Once in the fourth stage, diabetic nephropathy is irreversible and can reduce albuminuria by various means, but albuminuria cannot be eliminated.

Most patients develop high blood pressure and glomerular filtration rates begin to decrease. Diabetic nephropathy continues to develop, resulting in decreased renal function and, ultimately, it develops into renal failure. Diabetic lesions are constantly evolving and can be delayed by appropriate interventions. In the fifth period for end-stage renal failure, the common characteristic is glomerular capillary occlusion, associated with glomerular hyalinization; in this stage glomerular filtration rate is very low and nitrogen retention, hypertension occur, renal replacement therapy (hemodialysis, peritoneal dialysis or renal transplantation) can be carried out for the treatment.

Not every diabetic patient goes through these 5 stages. On the contrary, most of the patients only stay in the first two stages, but showing no obvious renal damage after 20-30 years. However, once developed to the third stage, the microalbuminuria stage, it is likely to continue to develop in the four phase, showing typical diabetic nephropathy manifestations. Treatment should try to keep the disease staying in third stage; once in the fourth stage, the course of disease is irreversible, the vast majority of patients will enter the end-stage renal failure. Therefore, diabetic nephropathy patients should get early detection, early prevention and early treatment, do not wait until it is to serious to pay attention to.

Early detection and early treatment for diabetic nephropathy

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