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How to reduce the blood pressure in patients with kidney consolidation?

2017-06-08 16:29

About half of the patients with nephrotic syndrome have mild hypertension, and when the edema subsides or subsides, it can return to normal. Therefore, mild hypertension can not be treated. If the blood pressure is above 21.3 / 13.3kPa and the blood pressure does not return to normal after the swelling, antihypertensive treatment should be taken. The commonly used antihypertensive drugs are as follows:

(1) angiotensin converting enzyme inhibitors: the antihypertensive mechanism of this kind of drugs mainly through inhibiting angiotensin converting enzyme activity, reducing the level of angiotensin II, relaxation of small arteries and so on, to achieve the purpose of reducing blood pressure. This leads to renal hypertension due to kidney disease caused by the increased renin secretion has good antihypertensive effect, in addition, there are certain deterioration of renal function, reduce proteinuria and glomerulosclerosis, so for clinical use.

The captopril orally 1 times: 25 ~ 50mg, 3 times a day.

Benazepril (Luo Tingxin): Oral 1 times 10mg, 1 times a day, according to the condition can be increased to 40mg per day.

(2) calcium antagonists: many studies have confirmed that these drugs have the function of reducing blood pressure and delaying the deterioration of renal function.

Nifedipine: Oral 1 times, 5 ~ 10mg, 2 to 3 times a day.

The amlodipine (Norvasc): 5mg 1 times a day, the maximum daily dose of 10mg, oral.

(3) P receptor blockers: the drugs except by reducing cardiac output and blood pressure, and reduce the role of the renin, renin dependent hypertension has better curative effect, and does not affect the renal blood flow and glomerular filtration rate.

Beauty: take orally 1 times 50 to 200mg, 1 times a day.

Atenolol: take orally 1 times 50 ~ 100mg, 1 times a day.

(4) vasodilator hydralazine, prazosin, etc. can be selected, the former general 200mg daily, the daily 6 ~ 12mg.

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