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Nephrotic syndrome = nephrotic syndrome?

2017-06-08 16:15

Many people think that the nephrotic syndrome is a single disease to sign written or entered as nephrotic syndrome, nephrotic syndrome, in view of the people for the nephrotic syndrome and renal disease medical knowledge in terms of cognitive misunderstanding, it is necessary for us to put the nephrotic syndrome with nephrotic syndrome syndrome term battle decomposition clear.

First of all, it is important to point out that the "syndrome" of nephrotic syndrome is an "error" of "Zheng". Nephrotic syndrome is not a disease or symptom of kidney disease, but a group of clinical syndromes of kidney disease. It is a common clinical manifestation of glomerular diseases (including glomerulonephritis, nephropathy, lupus, and others). For primary glomerular disease with nephrotic syndrome, it is difficult to identify the cause of the disease and may be diagnosed as nephrotic syndrome temporarily, and the etiology and / or pathological diagnosis should be determined as soon as possible. In the field of renal medicine, the term nephrotic syndrome has not yet been used to generalize the single kidney disease.

What is nephrotic syndrome?

Christian (Christiansen) in 1932 with nephrotic syndrome (nephroticsyn drome nephrotic syndrome) the term, due to a variety of generalized renal damage in severe proteinuria, and a corresponding set of clinical manifestations, these manifestations and nephropathy is very similar, named kidney disease syndrome. Its most basic feature is massive proteinuria. At present, our country's definition is = 3, 5g / d. Most of the foreign as more than 3 (or 3, 5g, 0g) /1, 73m2/d. Often accompanied by hypoproteinemia (less than 30g), edema, hyperlipidemia.

So, what are the symptoms of nephrotic syndrome in those diseases of the kidney? What are the nephrotic symptoms outlined in nephrotic syndrome?

Nephrotic syndrome can occur almost all of which can cause glomerular diseases. According to clinical practice, it can be pided into two categories, primary and secondary. Primary nephrotic syndrome is caused by an initial lesion occurring in the glomerulus. Primary glomerular diseases, acute glomerulonephritis, acute nephritis, chronic glomerulonephritis can occur in the disease process of nephrotic syndrome, which can cause the. Pathologically, minimal change nephropathy, mesangial proliferative glomerulonephritis, membranous nephropathy, glomerular focal segmental sclerosis, and mesangial capillary nephritis are all associated with nephrotic syndrome. Secondary nephrotic syndrome, which is secondary to systemic diseases, such as diabetic nephropathy can, lupus nephritis, renal amyloidosis, infection, drug disease, connective tissue disease and some genetic diseases caused by nephrotic syndrome.

The main clinical symptoms of nephrotic syndrome are as follows: (1) proteinuria: the daily urinary protein in adults exceeds 3 and 5g, which is the first essential feature of nephrotic syndrome (five). The main component of the urine protein is albumin. (2) hypoalbuminemia: albumin lower than 30g/L, which is the second essential characteristics of nephrotic syndrome, mainly caused by the excretion of a large amount of serum albumin. (3) hyperlipidemia: plasma cholesterol, triglyceride, low-density lipoprotein and very low density lipoprotein can be increased significantly. (4) edema: the edema degree of nephrotic syndrome is different, the most obvious is the loose tissue. Usually there is high edema. (5) hypertension: adult nephrotic syndrome, about 20% to 40% of hypertension. It is usually moderate, often between 18, 7~22, 7/12, 7~14, and 7KPa. The first two are prerequisites for the diagnosis of nephrotic syndrome.

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