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Clinical manifestations of chronic renal failure

2016-12-29 19:11
Renal failure can be divided into acute renal failure and chronic renal failure. Early symptoms of chronic renal failure is not prominent, not easy to be diagnosed clearly, easy to missed diagnosis or misdiagnosis. But in the later stage, the lesions may involve the whole body. Here are some of the clinical symptoms of chronic renal failure.
1, toxic and accumulation of metabolites caused symptoms:
(1) the digestive system manifestations: digestive system performance is one of the earliest and most common, mainly of anorexia, indigestion. Who can have severe glossitis, oral erosion. If the digestive tract ulcer involving blood vessels can have haematemesis, hematochezia.
(2): the skeletal system due to calcium and phosphorus metabolism, can appear osteoporosis, osteomalacia or osteitis fibrosa and pain and pseudo fracture.
(3) neuropsychiatric symptoms: Central manifestations of unresponsive, depression, irritability, excitement, convulsions, lethargy and coma. Around the performance of peripheral nerve degeneration performance, skin allergies, pain, limb weakness and disability etc..
(4) manifestation of cardiovascular system: common hypertension, uremic pericarditis, myocarditis and arrhythmia and heart failure.
(5) skin manifestations: pale, dry, itchy, and "urea cream"".
(6) the performance of hematopoietic system: chronic renal failure patients with varying degrees of anemia, mostly due to long-term malnutrition, erythropoietin and hemolytic. Renal failure patients have bleeding tendency manifested as subcutaneous hemorrhage and ecchymosis, gingival bleeding, epistaxis, serious person can produce digestive tract bleeding and death. In addition, there are abnormal white blood cells, due to the "urotoxin" role, the generation and function of disorder of white blood cells, white blood cell counts decreased (mainly lymphopoiesis decrease), neutrophil chemotaxis ability, phagocytosis and killing of bacteria is also reduced.
(7) endocrine dysfunction: parathyroid dysfunction performance: mainly for hyperparathyroidism, can appear disorders of calcium and phosphorus metabolism, the uremic osteopathy changes; thyroid dysfunction due to T3 and free T3 index decreased, more performance loss for the thyroid function of the symptoms, such as fatigue, fatigue, sleepiness, dry skin, hearing loss, hyporeflexia, low temperature; sexual dysfunction: Women's performance by reducing the amount of menstruation, or even amenorrhea. The main manifestations of impotence and decreased sperm motility. Delayed onset of sexual maturation in children.
(8) the respiratory symptoms of respiratory system in general can have difficulty breathing in acid poisoning, can also produce bronchitis, pneumonia and pleurisy etc. by uremia.
Expert tip: usually must pay attention to, there is not timely medical treatment.
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