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What are the clinical manifestations of renal failure?

2016-12-29 18:16
What are the clinical manifestations of renal failure? Renal failure is developed to the stage of nephropathy, renal failure clinical manifestations with nephropathy patients do not understand, if we can timely understand the kidney disease symptoms, will block the renal fibrosis, prevent further kidney damage, avoid renal failure stage.
Clinical manifestation of renal failure
Renal failure clinical manifestations 1, the initial period
Patients with this disease often suffer from known causes of ATN, such as hypotension, ischemia, sepsis, and nephrotoxicity. But there is no obvious renal parenchyma injury. Acute renal failure is preventable at this stage. However, with the obvious damage of renal tubular epithelial cells, GFR suddenly declined, the clinical manifestations of acute renal failure syndrome became apparent, then entered the maintenance period.
Clinical manifestations and maintenance of renal failure
Less urine period. Typical for 7-14 days, but can be as short as a few days, up to 4-6 weeks. Glomerular rate remained low. Oliguria (<40Oml/d) may occur in many patients. However, some patients may not have less urine, urine volume of 400ml/d or more, known as non oliguria acute renal failure, the majority of their illness is lighter, the prognosis is better. However, whether or not the volume of urine decreased, with the decline of renal function, a series of clinical manifestations of uremia. Infection is another common and serious complication of acute renal failure. At the same time in acute renal failure or in the development of the disease can also be combined with multiple organ failure, the mortality rate can be as high as 70%.
Renal failure clinical manifestations 3, recovery period
Renal tubular cell regeneration, repair, recovery of renal tubular integrity. Glomerular filtration rate gradually returned to normal or near normal range. Oliguria patients began to appear diuretic, can have polyuria performance, daily urine volume up to 3000-5000ml, or more. Usually lasts 1-3 weeks and then returns to normal. In contrast to glomerular filtration rate, the recovery of glomerular epithelial cell function (solute and water reabsorption) is relatively slow and often takes several months to recover. A small number of patients may eventually be left with varying degrees of renal structural and functional defects.
To sum up, is the clinical manifestations of renal failure, if these symptoms of kidney disease patients, it should be timely treatment, scientific treatment, to avoid entering the uremia period.
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