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The main causes of chronic renal failure

2016-12-29 11:34

Chronic renal failure is a chronic disease. At first, the performance was not very obvious. Some patients with chronic renal failure, there were no obvious symptoms in patients with chronic kidney disease, easily misdiagnosed as digestive tract diseases, tumor diseases, regeneration of aplastic anemia, peripheral neuritis, and delayed treatment, do not be fooled by the illusion of chronic renal failure. Chronic renal failure (CRF) is caused by a variety of chronic progressive renal irreversible damage, and to leave, full of toxin of water and electrolyte, renal anemia and calcium phosphorus metabolism disorder as the main manifestations of the syndrome in a group. Chronic renal failure is a serious stage of renal insufficiency. Can cause renal failure on the human body injury is very large, more likely to lead to death. What are the causes of renal failure?
The main causes of chronic renal failure are various types of primary glomerulonephritis; secondary to systemic disease; chronic kidney disease; chronic urinary tract obstruction; congenital renal disease.
The main manifestations of chronic renal failure is the decline of renal function, retention of metabolites, water electrolyte and acid-base imbalance, leading to the kidney can not maintain the stability of the human environment.
According to the group of Chinese Journal of internal medicine of kidney disease in June 1992 to determine the criteria for chronic renal failure can be divided into four stages:
First stage (renal insufficiency compensatory phase): glomerular filtration rate (GFR) of 50 ~ 80ml/min (clinical commonly used creatinine clearance rate to represent GFR), serum creatinine (Scr) from 133 to 177umol/L.
The second stage (renal decompensation): GFR20 ~ 50ml/min, Scr186 ~ 442umol/L.
Third stage (renal failure stage): GFR10 ~ 20ml/min, Scr ~ 451 ~ 707umoll/L.
Fourth stage (uremia stage or end stage of renal failure): GFR<10ml/min, Scr>707umoll/L.
The symptoms of chronic renal failure complicated with renal insufficiency, the early symptoms of the disease, only the original, can only be found in muscle clearance decreased, urine concentration value function and decrease C and phenolsulfonphthalein excretion rate of uremia organs and tissues in the inspection, performance for the digestion step, heart spirit dish nervous system, pipe, made dish system and respiratory system function disorder, and hyponatremia in water and fat retention, low calcium Ib disease and hyperphosphatemia and metabolic acidosis, water electrolyte, acid-base disturbance performance.
Expert tip: we have to go to the hospital when there is a physical examination, the conditions of the annual physical examination.

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