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What is renal failure?

2016-12-29 10:10
A lot of people know that renal failure, but we know what is the specific renal failure? Renal failure is a kind of pathological state of partial or total loss of renal function. It can be divided into two kinds of acute renal failure and chronic renal failure. Here we introduce acute renal failure.
Acute renal failure due to various diseases, resulting in two loss of renal excretory function in a short period of time, referred to as acute renal failure, showed little or no urine, electrolytes and acid-base imbalance and sudden uremia. There are also non oliguria type of treatment in a timely manner appropriate renal function can be restored to the complex condition of critically ill patients or treatment can not be converted into chronic renal insufficiency or death.
Acute renal failure includes the following:
Because of the lack of blood volume or the insufficiency of heart function, the results showed that the renal blood perfusion was not enough
The kidney of acute renal failure due to renal disorders in severe acute glomerular disease of acute interstitial disease of acute renal tubular necrosis in acute renal vascular disease and chronic kidney disease in some incentives under the action of the two acute deterioration of renal function in acute renal tubular necrosis was the most common.
The results showed that the acute obstruction of the urinary tract caused by the tumor of the stone or the hypertrophy of the prostate resulted in the increase of urine and blood urea nitrogen.
What is the cause of acute renal failure?
Renal ischemia and kidney poisoning caused by various factors of prerenal azotemia caused sustained renal ischemia and hypoxia; renal toxicity of various substances such as bacterial endotoxin drugs and biological effects of toxic heavy metals in kidney can cause errors in addition type transfusion and drugs can cause acute intravascular hemolysis, crush injury, burns and severe myopathy. Can block the tubules for hemoglobin and myoglobin, and the occurrence of acute tubular necrosis and acute renal failure, acute renal failure pathogenesis is still unknown. Acute renal tubular injury theory can not be satisfactorily explained. In recent years, it has been suggested that the changes of renal hemodynamics induced by the release of the active substances of vascular contraction and the intracellular calcium influx and oxygen free radicals play an important role in the pathogenesis of acute renal failure.
Clinical manifestations of acute renal failure:
Acute renal failure clinical manifestations of oliguric acute renal tubular necrosis stage: oliguria: urine volume decreased resulting in the occurrence of hyperkalemia (severe edema, water intoxication, elevated blood pressure, pulmonary edema or cerebral edema) metabolic acidosis and acute symptoms of uremia, hyperkalemia and water poisoning was the main cause of death of polyuria stage: the regeneration of renal tubular epithelial cells after repair of urine volume increased gradually, the serum potassium, low blood sodium, persistent polyuria patients may die of dehydration and electrolyte disorder and recovery phase: polyuria period after the urine volume reduced to normal.
Different causes of acute renal failure according to the original symptoms and signs of the disease can also be diagnosed, who can not determine the cause of disease and treatment options should be as soon as possible renal biopsy.
Acute renal failure (CRF) is a kind of acute renal failure. This is a disease caused by a variety of causes of acute kidney injury, within a few hours or days to nephron regulating function decreased dramatically, so as not to maintain fluid balance and electrolyte excretion of metabolites, and cause hyperkalemia, metabolic acidosis and acute uremia syndrome, the clinical syndrome known as acute renal function failure. The rapid development of acute renal failure patients in the early stages of the disease should pay attention to, as soon as possible as soon as possible to the hospital for treatment, but also as far as possible to reduce kidney damage.
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