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24-hour urinary protein quantification with random urinary p

2017-03-03 15:05

 

Kidney disease needs to evaluate the amount of urinary protein excreted, the 24-hour urinary protein excretion rate is recognized as the gold standard, but 24-hour urinary protein quantification is often inaccurate. Because many links are factors that affect the 24-hour urinary protein quantification:

Leaving the urine is not complete, because the urine when the stool is difficult to collect; there will be forgotten to collect and so on;

Preservative effect, because the urine protein or urine sugar, will breed bacteria, urine deterioration, often need to add preservatives in the urine, commonly used preservatives are sodium nitrogen, formalin, hydrochloric acid and so on. These preservatives themselves will lead to protein denaturation;

When the inspection, did not stir well;

24 hours too long, inconvenient patients wait until the results.

This prompted clinical workers to find a way to replace the 24-hour urine protein quantitative method, random urine protein / creatinine ratio is currently used instead of 24-hour urine protein quantitative method. It has a very strong correlation with the 24-hour urinary protein excretion rate. Random urine protein / creatinine ratio can be used as one of the important methods to exclude significant proteinuria (urinary protein excretion rate greater than 300mg / 24h), using this method May reduce the collection of unnecessary 24-hour urine.

 

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