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What are the suggestions for the treatment of Henoch-Schonlein purpura nephritis?

2018-02-13 18:09

Many patients with Henoch-Schonlein purpura are very troubled after suffering from nephropathy. The external treatment of skin diseases has left them exhausted and unseen nephropathy, as if the whole person had fallen into despair.

Allergic purpura and renal involvement, appear abnormal urine, the urine test results will appear or occult blood protein, which is purpura nephritis, and as soon as the development of purpura nephritis, disease treatment increased the difficulty of the course will be extended, often give people an incurable feeling. Each stage of Henoch Schonlein purpura nephritis and its treatment:

What are the suggestions for the treatment of Henoch-Schonlein purpura nephritis?

Stage one: slight kidney damage, only intermittent treatment. Urine occult blood: with purpura therapy, the use of antihistamine drugs, such as antibiotics, serious person can use hormone, immunosuppressants. In addition, we also need to use traditional Chinese medicine conditioning, enhance immunity, can make the patients in a long period.

Stage two: mesangial proliferation, urine occult blood become persistent, some patients may appear a small amount of urine protein. Treatment: if only the same with the treatment of urinary occult blood, a period; if the urine protein and use of angiotensin-converting enzyme inhibitors or angiotensin receptor antagonists, usually do not use hormone.

Stage three: mesangial proliferation and 50% glomerular crescent formation, renal symptoms gradually worsened, and some patients presenting as nephrotic syndrome. The treatment of this stage due to urinary protein increase, began to use hormone, the situation is more serious in patients with the use of cyclophosphamide. In addition, in addition to reducing the drug treatment of traditional Chinese medicine side effects can also inhibit glomerular epithelial cell proliferation, reduce the crescent formation rate.

Stage four: mesangial hyperplasia, and 50% to 75% glomerular crescentic formation, and renal symptoms aggravated further. For treatment: hormone combined with cyclophosphamide is most common. Some patients with acute progress can also use hormone shock therapy.

Stage five: mesangial hyperplasia, and more than 75% glomerular crescentic formation, severe impairment of renal function, began to appear heart failure, anemia and other complications. Treatment: similar to the four stage, some patients with acute progression of the disease can also be treated with plasma exchange.

Stage six: "false" membranoproliferative glomerulonephritis and membranoproliferative glomerulonephritis is the precipitation of IgA mesangial proliferative nephritis, but the treatment difficulty and harm and treatment. The same membrane nephropathy: into the end stage, based on conservative therapy, due to renal function is severely damaged, the use of alternative dialysis machine and combined with traditional Chinese medicine treatment, physical conditioning.

Henoch Schonlein purpura is usually damaged by Henoch Schonlein purpura, and its severity is severe. However, with the repeated attack of purpura, the delayed treatment and the aggravation of kidney injury, the treatment of this disease is also difficult. Meanwhile, the prognosis is also quite different.


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