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Is lupus erythematosus associated with infection?

2017-09-10 17:11

We all know that lupus erythematosus is a common disease in life, and in recent years, the incidence of lupus erythematosus gradually increased, according to experts, can cause lupus erythematosus for many reasons, then lupus erythematosus and infection?

Some people think that the incidence of lupus erythematosus and some viruses (especially lentivirus) infection. C virus antibodies were isolated from lupus erythematosus model mice. Especially in patients with lupus erythematosus glomerular endothelial cell plasma, vascular endothelial cell lesions can be found in similar inclusion bodies of the material, while patients with elevated serum antibody titer. Especially for measles virus, parainfluenza virus i, ii type, eb virus, rubella virus and so on. In addition, in patients with serum, anti-rna antibodies and anti-double-stranded dna and other antibodies exist.

However, these inclusion bodies can only be found in the tissues infected by the virus, and under electron microscopy, these inclusion bodies are observed to have a tubular reticular structure. But these inclusion bodies can also be seen in dermatomyositis, scleroderma, acute sclerosing total encephalitis, and attempts have been made to isolate the virus from tissues with inclusion bodies, but have not been successful. So until now has not been found in the incidence of human lupus erythematosus and any pathogens are directly related.

It is speculated that the pathogen may only be a stimulus for b lymphocytes, triggering the disease. Nevertheless, in clinical work, we do find that both bacterial and viral infections can aggravate the symptoms of lupus patients or relapse in patients who are already in remission. Therefore, active prevention and treatment of infection, is an important part of the control of lupus activity, lupus erythematosus patients, in general should pay attention to prevent all infections, so that the disease tends to be stable.

Is lupus erythematosus associated with infection?

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