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Tongshantang experts talk about lupus nephritis and IgA nephropathy

2017-08-05 17:24
Lupus nephritis (LN) and IgA nephropathy are the most common secondary and primary renal diseases in China, and are the leading cause of end-stage renal disease. The etiology of Iga nephropathy is unknown. The types of lesions include focal segmental lesions, capillary proliferative lesions, mesangial proliferative lesions, crescentic lesions and sclerosing lesions. Its clinical manifestation is recurrent attack of gross hematuria or microscopic hematuria, accompanied by varying degrees of proteinuria, and some patients may have severe hypertension or renal insufficiency.
In patients except with lupus nephritis in kidney, and also have other systemic manifestations, such as rash, joint pain, oral ulcer, alopecia, serous effusion, blood immune examination showed anti ANA, anti dsDNA antibody positive, hypocomplementemia, renal biopsy immunofluorescence persity, often for a variety of immune globulin deposition. Inpidual patients with systemic lupus erythematosus, immunofluorescence results are not typical of all bright, but by the IgA deposition, light microscopy showed mesangial proliferative glomerulonephritis, the renal pathological diagnosis should be considered as a IgAN, instead of LNI/II.
Need note that, in patients with lupus nephritis should avoid exposure in the sun, because of systemic lupus erythematosus patients if the exposure in the sun or by other rays or artificial light sources such as incandescent lamp irradiation, can make the patient facial erythema is aggravating, or exposed skin red macules and papules, or bullous rash accompanied by burning sensation the pain, itching, or systemic symptoms, this phenomenon is called "light sensitive" phenomenon.
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Tongshantang experts talk about lupus nephritis and IgA nephropathy

 
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