home >>

What are the therapeutic methods for acute tubulointerstitial nephritis?

2017-05-26 14:13

Acute tubulointerstitial nephritis is an acute renal failure syndrome mainly affects renal tubular and interstitial nephritis. What are the treatment method of acute renal tubule? This is the patients concerned with this question, we look at the following introduction.

What are the treatment method of acute nephritis renal tubule? When the causative drugs removed, renal function can often be recovered (especially in the first 6~8 weeks), though often some residual scar. Oliguria treatment is recommended for a long time. When severe nephritis acute tubule is caused by allergy or immune response when corticosteroids (such as prednisone 7~10 day 1mg/kg daily application for 3 days, then gradually reduced) can promote recovery of renal function.

However, recovery may be incomplete with azotemia is consistently higher than the baseline. In this patient, rather than diffuse patchy interstitial infiltration, the prednisone reaction delay and continuous ARF (> 3 weeks) that irreversible damage. If the cause can be identified and removed, histological changes are usually reversible. But some serious cases may progress to fibrosis and renal failure.

Acute tubulointerstitial nephritis is different, but the typical performance is temporary and medication or infection of acute renal failure associated with or without oliguria. Fever occurred in most cases, may be accompanied by urticaria rash. Usually white blood cells in urinary sediment, red blood cells and white blood cells of tube, but there can be no exception more than 75% cases. At the same time appear in the blood and urine of eosinophils (Hansel staining). The urine protein is usually small. Non steroidal anti-inflammatory drug induced diseases, often lack the typical fever, rash and eosinophilia.

Many patients have signs of tubular dysfunction, such as urine (concentrated defects), reduced capacity (Na, save the defect of hyperkalemia (K) excretion defects) and metabolic acidosis (acid excretion defects). Because renal interstitial edema is usually larger and excessive absorption of radioactive gallium or radionuclide labeled white blood cells. However, 67, gallium radionuclide scan negative can't exclude the diagnosis.

please leave a message if you have questions,experts will reply to you soon,and help you relieve the pain.
  • Related Articles
Join over 37,000 people who receive bi-weekly professional nephropathy guidance.