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Why patients with glomerular nephritis have less urine?

2017-03-10 08:42

Glomerulonephritis is a common kidney disease, pided into acute glomerulonephritis and chronic glomerulonephritis two kinds, the typical symptoms of glomerulonephritis is less urine. So, why dose patients with glomerular nephritis have less urine?

Experts pointed out that the reasons for the lack of urine in patients with glomerulonephritis:

1, the early stage of acute glomerulonephritis, due to the body's immune response and inflammatory response, so that the body small arteries, including renal vasospasm  appear significant ischemia, the effective filtration pressure of the capillaries to reduce, reduce urine production.

2, the immune response caused the glomerular basement membrane non-specific inflammatory damage, so that the basement membrane thickening, swelling or rupture, resulting in decreased of glomerular filtration area, filtration rate decreased, the formation of urine reduced.

3, hyperplasia and swelling of glomerular capillary endothelial cells, glomerular epithelial cells and capillary interstitial cell, may be a compensatory response of the body againsting basement membrane injury, but when the cells hyperplasia and swelling, there are the infiltration of polymorphonuclear leukocytes and fibrin deposition, resulting in a narrow lumen, even so blocking, blood flow blocked,  ischemia, glomerular filtration reducing,Causing glomerulonephritis

Experts advise: Patients with glomerulonephritis must be treated in time, long-term accumulation of toxins in the body, will seriously affect the health of the kidneys, and even worsen for uremia. At present, for the treatment of glomerulonephritis mostly adopt hormone, although can control the proteinuria in a short time, relieve the complications, but it is easy to relapse. Moreover, long-term medication has many side effects.


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