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The first cause of uremia glomerulonephritis

2017-03-02 11:50

Early cause

1 nephritis is pided into primary and secondary of the two categories, there is a large number of proteinuria when called nephrotic syndrome. Primary glomerulonephritis refers to the inflammation of the glomerulus itself, and is pided into two kinds of acute and chronic, chronic nephritis can also be pided into a variety of pathological types, IgA nephropathy is the most common. Secondary nephritis refers to other parts of the body caused by nephritis. Almost all diseases of the body can cause nephritis, and kidney disease is often the most important factor to determine the severity of the disease, such as systemic lupus erythematosus and vasculitis. The common diseases caused by nephritis include autoimmune diseases such as lupus erythematosus, rheumatoid arthritis, vasculitis, Sjogren syndrome; allergic purpura; infection, tonsillitis, such as hepatitis especially hepatitis B; tumor; drug. To find the cause from so many diseases, we must fully understand the various manifestations of the disease, targeted screening, necessary for renal biopsy, sometimes miss a very small details, will lead to wrong diagnosis, delayed treatment of the disaster.

Accurately determine the condition

2 etiology must also accurately determine the severity of the disease, including the basis of the degree of proteinuria and hematuria, with or without hypertension and impaired renal function, and often the most important is to change the degree of renal biopsy, such as IgA nephropathy and lupus nephritis can according to the pathological change degree is pided into several subtypes. Treatment decisions based on pathological subtype. Therefore, it is very important for the diagnosis of renal disease, the diagnosis of the disease and the treatment plan. When systemic lupus erythematosus (SLE) is characterized by proteinuria, hematuria, or abnormal renal function, it is necessary to perform a renal biopsy.

Active and effective treatment

The 3 mechanism of nephritis is that part of the early stages of the disease played a major role in the immune inflammation, therefore to inhibit inflammation, can choose appropriate drugs and disease lesions in different degrees, including hormones and immunosuppressive agents. Mention hormones, we all know that it has a lot of side effects, so the doctor in order to accurately understand the condition to determine whether the use of hormones and dosage and time to achieve the best results and minimal side effects. Some types of some diseases and some diseases with hormone effect is not good, still need to add other immunosuppressive drugs, these drugs more varieties, in recent years the new drugs, but have certain side effects.

In the occurrence and development of nephritis and many factors play an important role, such as oxidation, coagulation, glomerular hypertension, need to use a variety of drugs, scientific diet, exercise and other methods from all aspects of disease control. Only in this way can we get the best therapeutic effect.

Long term follow-up

4 in addition to inpidual cases of acute nephritis, the majority of nephritis is a chronic disease, the need for long-term treatment and follow-up, the main purpose of the three.

First, the recurrence of the disease should be treated in time. Some patients in the process of drug reduction or withdrawal of exacerbations, some in the withdrawal and the stability of the disease for several years or even decades after relapse.

Second, when the disease changes to adjust the treatment plan. The pathogenesis of nephritis is very complex, and different mechanisms play different roles in different stages of disease. Therefore, the application of drugs should be carried out under the guidance of a specialist, can not be sloppy.

Third, the sensitivity of nephritis patients to many adverse stimuli is very high, especially the drugs need to be cautious, because some drugs are toxic to the kidney, mainly cold medicine, analgesics, antipyretics, antibiotics and traditional Chinese medicine. In addition, colds, pneumonia, tonsillitis and diarrhea may also cause nephritis recurrence or aggravation. When the above situation should be to the Department of nephrology. A cold is not easy to get nephritis.

Acute nephritis

5 acute nephritis in children, after treatment in more than one year. Most of the chronic nephritis, such as not active treatment, the condition will continue to increase, and even evolve into uremia. Therefore, if the misdiagnosis of chronic nephritis acute nephritis, the consequences will be unbearable to contemplate. But in fact, this situation often happens, just the past two years, nephritis and renal biopsy and follow-up outpatient service ", we have already encountered hundreds of cases of such patients. Some patients with chronic nephritis after treatment can be stable for a long period of time, during which all urine and blood tests can be normal, then it is likely to be mistaken for acute nephritis cured. Therefore, we should remind you that you or your family and friends, such as had had acute nephritis, then please do a careful examination of the kidney.

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