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What prompted the existence of chronic renal failure can be

2017-11-16 15:20

Chronic renal failure (CRF) is a common and serious disease in clinic. Due to the lack of specific symptoms in the early stage, most of the patients did not cause enough attention, and once the symptoms were obvious, they were mostly in the late stage of disease - chronic renal failure uremia, and could only rely on lifelong dialysis or kidney transplantation to maintain life.

What prompted the existence of chronic renal failure can be restored hope?

However, there are some clinical cases of renal function in renal failure, there are still some recoverability, timely detection of these cases, early treatment, to save the patients with impaired renal function, improve the patient's quality of life, has very important significance to reduce the huge medical expenses caused by renal failure. The following may indicate the possibility of reverse recovery:

Activity with underlying lesions. Such as lupus nephritis, vasculitis associated nephritis, crescentic nephritis.

Obstruction factors: such as urinary calculi, tumor, prostatic hypertrophy caused by urinary retention, hydronephrosis and so on.

There are complications: if patients with severe infection, heart failure, severe hypertension and so on, can rapidly deteriorate the renal function, and timely correction of these factors can make the renal function to varying degrees of recovery.

The presence of renal hypoperfusion in the body, such as dehydration, hemorrhage, hypotension, shock, etc.. Severe diarrhea, vomiting, excessive sweating, poor eating, massive hydrothorax and ascites, hypoproteinemia and so on may lead to renal hypoperfusion, and urine volume decreases rapidly.

Drug factors: drugs leading to the body's allergic reactions, drugs that cause nephrotoxicity easily cause renal tubular cell poisoning, necrosis or tubulointerstitial inflammatory reaction, so that the rapid decline of renal function.

The pathological changes of renal biopsy showed that the main pathological changes were active lesions, the proliferation of glomerular cells was obvious, the sclerosis was less, the inflammatory cells were mainly infiltrated in renal interstitium, and the fibrosis was not serious. The clinical manifestations showed slight increase in serum creatinine and no significant reduction in the kidney.

Therefore, for patients with renal failure for the first time, the history of the disease must be examined in detail, and the renal function reversible factors should be carefully analyzed. Especially for patients with normal or slightly larger renal volume, more attention should be paid to the presence of acute and active renal lesions, and renal biopsy should be performed against time and time in order to confirm the diagnosis as early as possible and to gain valuable time for targeted treatment.

 

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