Patients with systemic lupus erythematosus after standardized treatment can gradually stabilize the state of the disease, drugs can be gradually reduced. But due to a variety of factors (such as have a cold, infection, pregnancy, surgery, fatigue, mental ...
Patients with systemic lupus erythematosus after standardized treatment can gradually stabilize the state of the disease, drugs can be gradually reduced. But due to a variety of factors (such as have a cold, infection, pregnancy, surgery, fatigue, mental shock, sunlight exposure. Stop drug and so on), disease can happen repeatedly, part of person changes activity period from stable period. So what circumstance should we consider disease change, namely relapse? We can judge by clinical symptoms and laboratory tests.
If you encounter the following circumstances, should consider disease review, timely consultation:
1. Fever of unknown origin: fever cannot be explained by common cold, respiratory tract infection, urinary tract infection, gastrointestinal tract infection or other causes;
2.Newly appeared rash, especially vasculitis rash at the end of the finger (toe);
3. New ulcer foci in the mouth and nose;
4, hair loss;
5. recurrent joint swelling and pain;
6. pleural effusion or pericardial effusion which can not be explained by other reasons;
7, swelling and proteinuria increased;
8, leukopenia or thrombocytopenia or anemia aggravation;
9. symptoms of nervous system, such as dizziness, headache, vomiting, convulsions, etc.
10. Check ANA (antinuclear antibody), anti-double-stranded DNA antibody was increased.
11, ESR increased rapidly;
12.The complement decreased, especially C3.
We ask the patients to return to hospital regularly and check their blood. The purpose is to detect the change of the disease early, to make the diagnosis of the disease recurrence in time, to adjust the medication, and to avoid delaying the disease, complement and ANA. Anti-double-stranded DNA antibody is a commonly used laboratory index to judge the activity of systemic lupus erythematosus, but we can not only see the abnormal test results is definitely lupus recurrence, need to comprehensive analysis of any other reasons. In order to avoid misjudgment, the treatment direction is skewed, and even serious accidents occur. Therefore, we are reminded that the patients can get a good prognosis after the symptoms appear in time, early and reasonable treatment can make the patients get a good prognosis.
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