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What are the complications of nephrotic syndrome in children?

2017-09-22 16:53

The symptoms of nephrotic syndrome in children are mainly due to the large amount of proteinuria, hyponatremia, hyperlipidemia and edema of varying degrees, edema of nephrotic syndrome in children with double, edema of lower extremities, and frequent complications of nephrotic syndrome in children presented as follows:
Infection: because of the loss of large amounts of plasma protein immunoglobulin urine, is reduced, affecting the formation of antibodies. The application of adrenal cortical and cytotoxic Yao causes the body of the patient resistance decline, and is very easy to develop infections, such as skin infections, Primary peritonitis, respiratory tract infection, urinary tract infections, septicemia and even induce.
Coronary heart disease: Children with nephrotic syndrome often have hyperlipidemia and high blood condensation status, so it is easy to have coronary heart disease. Some people reported that the incidence of myocardial infarction in patients with nephrotic syndrome was 8 times greater than that of normal people. Coronary heart disease has become the third leading cause of death in nephrotic syndrome (post-infection and renal failure).
The formation of thrombi: the incidence of thrombosis in children with nephrotic syndrome is easy to occur, especially the incidence of membranous nephropathy can reach 25% ~ 40%. The cause of thrombosis is edema, low activity of patients, the ecstasy of the vein, high blood fat, blood concentration, high fibrinogen content, V, VII, Ⅷ, X Factor increase and use of cortical adrenal hormone, and blood is prone to high state of coagulation, etc.
Acute renal failure: in children with nephrotic syndrome due to the large amount of proteinuria, low, hyperlipidemia, in the body often in low blood volume and high coagulation status, vomiting, diarrhea, use of antihypertensive drugs and diuretics diuretics large amount of diuretic, can make renal blood volume perfusion reduced suddenly, and thereby reduce the rate of glomerular filtration, which leads to acute renal failure.In addition, nephritic syndrome when renal interstitial edema, protein concentration to form a tube tubular renal block and other factors, can also induce acute renal failure.
Electrolyte and Metabolic Disorder: repeated use of diuretics or reasonable long-term salt, may cause children with secondary nephrotic syndrome hyponatremia; the use of cortical adrenal hormone and a large amount of diuretics lead to a large amount of urine, if not timely potassium supplement, easy to appear hypokalemia.

What are the complications of nephrotic syndrome in children

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