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What check patients should do with nephrotic syndrome?

2017-09-19 15:07

In recent years, although the standard of living has improved considerably, but various diseases are constantly cropping up, especially the nephrotic syndrome is common in our life. So for this type of diseases, we must actively do good inspection and treatment, down first to understand nephrotic syndrome should patients do what I have to do?
Laboratory exam
Urine simple urine nephropathy routine, the qualitative protein in the urine is more than ~; the amount of 24 h was more than 0.1 g / kg, and occasionally a small amount of red blood cells. In addition to varying degrees of proteinuria, nephritis nephropathy can also be seen under the microscope or hematuria.
The blood biochemical determination is characterized by low (serum albumin <30 g / l, infant <25g L = ""> 5.7 mmol / l, infant> 5 mmol / L).
Determination of oliguria renal function temporal phase may have mild nitrogen, simple renal function is normal. If there is a different degree of renal failure, increased serum creatinine and urea nitrogen, it is suggestive of nephritis nephropathy.
Determination of serum complement is useful to distinguish nephrotic syndrome and simple nephrotic nephrosis, the old serum complement is normal, the latter often have different degrees of complement low, C3 continue to reduce.
Serum and urinary protein electrophoresis showed urinary protein selectivity by detecting IgG in the urine, while the ratio of γ - globulin to urine albumin was less than 0.1, and more than 0.5 was non-selective proteinuria (suggestive nephrotic type) if the ratio of γ-globulin to albumin was less than 0.1.
Immune test and detection of anti - nuclear serum Antibody, anti - dsDNA Antibody, anti - SM Antibody, anti - RNP Antibody, anti - histone antibody, markers of hepatitis B virus and rheumatoid factor, circulating immune complexes, distinguish between primary and secondary nephrotic syndrome.
Detection of coagulation and fibrinolysis related proteins, such as blood ⅷ fibrinogen and V, VII and X, Ⅲ urinary antithrombin, fibrin degradation products (FDP) can reflect the state of coagulation of the body, and provide a basis for the anticoagulant treatment.
Determination of lysozyme, N-acetyl-β-amidogen (NAG) by the enzyme determination can help determine whether there is tubular renal interstitial damage - at the same time.
Other inspections
Examination of images such as B-ultrasound excluded congenital malformation of the kidney. Percutaneous renal biopsy in the diagnosis of nephrotic nephritis or treatment with glucocorticoids in poor patients should be timely to clarify the biopsy, pathological type to guide the formulation of the program of treatment.

What check patients should do with nephrotic syndrome

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