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What are the early symptoms of nephrotic syndrome?

2017-03-02 13:44

Nephrotic syndrome can be pided into 3 types according to different pathological features, primary nephrotic syndrome, congenital nephrotic syndrome and secondary nephrotic syndrome. The clinical manifestations of patients with nephrotic syndrome have 4 characteristics: massive proteinuria, edema, hypoproteinemia and hyperlipidemia. Here we give a detailed description of the clinical manifestations of nephrotic syndrome.

1, massive proteinuria

The main component of albuminuria is albumin and other plasma protein components. Patients with proteinuria more than 3.5 grams per day, may have lipid. When the glomerular filtration rate is reduced, proteinuria can be reduced, and the output of urinary protein can be increased when severe hypoproteinemia, high protein diet will increase the excretion of urinary protein.

2, edema

The most notable is the symptom of patients with progressive systemic edema, initial morning eyelid, face and ankle edema, along with the gradual development of the disease, edema can affect the body, and the emergence of ascites, pleural effusion, pericardial effusion, mediastinal effusion, edema of scrotum or labia, also can appear pulmonary edema.

3, hypoproteinemia

Hypoproteinemia refers to the patient's serum albumin per liter of less than 30 grams, when the patient's compensatory effect of albumin synthesis to compensate for the loss of urine protein, there will be hypoproteinemia.

4, hyperlipidemia

Hyperlipidemia is associated with hypoalbuminemia, patients showed urinary lipid, fatty body double refraction in urine, possibly for epithelial cells or fat body tube containing cholesterol.

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