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What are nephrotoxic drugs?

2017-07-17 15:36
We know that there are many reasons for kidney damage and kidney disease, including the use of random drugs. If you take nephrotoxic drugs, they can damage the kidneys. What are the nephrotoxic drugs?
Antipyretic analgesics. Also known as non steroidal anti-inflammatory drugs, common painkillers, cold medicine, rheumatism medicine, such as Bloven, An Naijin, indomethacin, Kangle Biyan tablets and acetaminophen.
Antibiotic drugs:
Aminoglycoside is a bactericidal drug, mainly used for systemic infection, streptomycin, gentamicin, amikacin and common stars belong to this category.
Amphotericin B is an antifungal agent.
Peptide antibiotics belonging to the class of polymyxin, mainly excreted from the kidney, but the excretion is slow; Bacillus peptide with severe kidney toxicity, only for local treatment; with vancomycin nephrotoxicity and ototoxicity.
Hypotensor. For example, diuretics such as thiazide are unsuitable for hypertensive patients with kidney disease, while Kato Pury class ACEI antihypertensive drugs may cause elevated serum creatinine.
Sulfonamides. Such as sulfadiazine, sulfamethoxazole, and so on. The elderly and those with renal dysfunction are cautious.
Methotrexate. Large doses can be deposited in renal tubules, leading to hyperuricemia, nephropathy, etc..
Cyclosporine. One of the most frequently used drugs in organ transplant patients,improper use can cause glomerular thrombosis, renal tubular obstruction, proteinuria, tubular urine, and so on.
Oral contraceptives. Women suffering from nephritis should not take them so as not to aggravate their condition.
Traditional Chinese medicine and proprietary Chinese medicine for kidney injury. Chinese medicine also has side effects, and now it is generally accepted that the traditional Chinese medicine containing aristolochic acid (such as gentian liver drop pill and Guan Mutong) has obvious nephrotoxicity. In addition, the common injury kidney herbs have mufangji, tetrandrine, Magnolia officinalis, Herba Aristolochiae, Kudingcha, cantharidin, fish bile, red lead, alum.
Compound Chinese medicine, diarrhea pill, a row of stone dragon liver bile powder, fenqing Zhilin pill, fukefenqing pills, Ganluxiaodu Dan, recurrence fufangzhenzhuanchuang tablets and deafness pill, angelica four inverse soup, xuanzhu lupus pill, Guanxinsuhe pill, pill, traumatic Duhuojisheng decoction has the risk of acute kidney injury.

What are nephrotoxic drugs

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