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What is the cause of diabetic nephropathy?

2017-10-15 15:42

What is the cause of diabetic nephropathy? Diabetic nephropathy is one of the most important complications of diabetes. If the diabetic patients with poor blood sugar control, it is likely to lead to kidney damage, causing diabetic nephropathy. The following is a detailed introduction of the causes of diabetic nephropathy.
Causes of diabetic nephropathy 1: high blood sugar
Diabetic nephropathy and hyperglycemia are closely related, poor blood glucose control can accelerate the development of diabetic nephropathy, good blood glucose control can significantly delay its development.
Causes of Diabetic Nephropathy 2: Hypertension
There is no direct relationship between hypertension and diabetic nephropathy, however, the elevation of blood pressure after the onset of hypertension or during the course of microalbuminuria may accelerate the progression of diabetic nephropathy and deterioration of renal function, aggravate urinary albumin excretion.
Causes of Diabetic Nephropathy 3: renal blood flow abnormalities
In the case of hyperglycemia, glomerular hyperperfusion, increased pressure, protein filtration increased, can also be deposited in the glomerular basement membrane, promote matrix proliferation, form a vicious cycle, and can cause nodular and diffuse glomerular sclerosis.
Causes of Diabetic Nephropathy 4: Genetic Factors
Studies have shown that the incidence of diabetic nephropathy in some diabetic patients with a family history of hypertension is obviously higher than patients without family history of hypertension. There is also a difference in the incidence of diabetic nephropathy among different races. All these indicate that the occurrence of diabetic nephropathy is related to genetic factors.

What is the cause of diabetic nephropathy

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