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What causes kidney failure

2016-12-25 10:57
Renal failure is a very common disease in our lives, renal failure is mainly divided into acute and chronic two, and the incidence of chronic renal failure is very high, more harm than acute renal failure. For the health of kidney failure patients, let me
Specific understanding, what causes renal failure?
(1) interstitial nephritis interstitial nephritis accounted for the incidence of chronic renal failure of the second. Tubular atrophy, fibrosis, scarring lead to reduced glomerular blood supply and renal dysfunction. Analgesic induced nephropathy, gouty nephropathy and antibiotics
And other nephrotoxic drugs induced nephropathy are interstitial nephritis.
(2) urinary tract of lower urinary tract obstruction under poor drainage, such as benign prostatic hypertrophy, or some anatomical defects caused by reflux of urine, renal pelvis dilatation, called hydronephrosis, compression of normal kidney tissues and cause renal failure.
(3) diabetic nephropathy in patients with a long course of diabetes, some people may have renal complications, especially in youth or type I diabetes patients can appear proteinuria, which is often the first indication of kidney involvement. Glucose in kidney disease
Approximately half of patients with urinary disease develop renal failure after 5 years, while other complications of diabetes.
(4) severe renal injury caused by other minor common diseases, resulting in chronic renal failure. Because the human body has a strong compensatory ability, can properly adjust the biological process of disorders. Sometimes we see only 10% of the remaining normal renal function
And still be able to sustain life.
Chronic renal failure:
1, chronic renal failure period. The glomerular filtration rate of 10--15 ml / min, renal function is severely impaired, patients have obvious clinical symptoms: obvious azotemia, metabolic acidosis, water and sodium retention, hypocalcemia, high blood phosphorus
Disease, obvious anemia, lack of concentration, easy to develop into uremia.
2, renal reserve loss period. Compensatory stage of chronic renal failure. This period glomerular filtration rate reduced to 30--60 ml / min, serum creatinine and urea nitrogen were normal or mildly high, although renal reserve capacity was lost during this period, but
The ability of the kidney to excrete metabolic wastes, regulate water electrolyte and acid-base balance can maintain the stability of the in vivo environment.
3, chronic renal failure uremia. Residual glomerular filtration rate of less than 10--15 ml / min, is the late stage of chronic renal failure. The symptoms of renal failure are more obvious, multiple body system damage and the corresponding symptoms, especially in the stomach
Intestinal, cardiovascular and central nervous system symptoms are more obvious. Serum creatinine, urea nitrogen increased significantly, water electrolyte imbalance, obvious metabolic acidosis, hyponatremia and Gao Jia blood, serum calcium significantly decreased, serum phosphorus increased, easy to
Endanger the patient's life.
4, the period of nitrogen. This period glomerular filtration rate of 25 ml / min, there is blood stasis that blood creatinine and urea nitrogen increased, kidney concentration function has mild damage, patients can have mild clinical symptoms, such as nocturia increased, mild anemia,
Easily overlooked. In this period, such as the body encountered insufficient blood volume, infection, renal toxicity drugs additional load, the renal function deteriorated rapidly, kidney failure and uremia.
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