Many patients with nephropathy know that high levels of creatinine are bad, but dont know how to judge by blood creatinine and how does kidney disease is staged. CKD1 phase: inflammatory phase. This phase of blood creatinine has no significant changes, re...
Many patients with nephropathy know that high levels of creatinine are bad, but don't know how to judge by blood creatinine and how does kidney disease is staged.
CKD1 phase: inflammatory phase. This phase of blood creatinine has no significant changes, renal function has not been damaged, commonly known as nephritis. This period is the most easily cured period, clinical indications for proteinuria, occult blood. Edema, hypertension.
CKD2 phase: compensatory phase of renal function. In this phase, the creatinine level ranges from 133-177 μ moI/L. At this time, half of the renal units are functioning normally. Can rely on their own compensatory function to meet the daily needs of the body.
CKD3 phase: decompensation of renal function. In this phase, creatinine levels range from 178-442 μ moI/L. Renal unit damage has exceeded 2/3 or more. The compensatory function of the kidney itself has been unable to meet the daily needs of the body. Most patients have begun to feel tired, but the symptoms are still not obvious. If you can get timely, regular treatment. There is still a 50% chance of clinical cure.
CKD4 phase: renal failure phase. When the serum creatinine exceeds 443 μ moI/L, it has entered the stage of renal failure, and the renal function has been reduced to an irreversible stage. At every moment, kidney cells are killed.
At this time many symptoms began to appear, such as anemia, dizziness, fatigue, nausea and so on. The focus of treatment has become to prevent the continued necrosis of renal cells, protect the remaining renal function. Some hospitals have also started advising patients on hemodialysis.
CKD5 phase: uremia stage. The serum creatinine level usually exceeds 707 μ mol / L during this period. In patients' kidneys, 90% of the kidney units are necrotic, and most of the kidneys shrink below 6 cm. And basically lost the function of producing urine.
Most of the patients have very strong symptoms, such as dizziness, fatigue, nausea, vomiting, heart failure, anemia and so on. Creatinine is the product of muscle metabolism in human body. Creatine is mainly produced by irreversible non-enzymatic dehydration reaction and then released into the blood. With urinary excretion. Therefore, the high level of serum creatinine is closely related to the total amount of muscle in the body and is not easily affected by diet.
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