What are the reasons for the occurrence of uremia, uremia is one of the diseases that affect our health, once the death is a lot of patients to face Fact。 However, in the face of such a disease, you do not worry, active and effective trea...
What are the reasons for the occurrence of uremia, uremia is one of the diseases that affect our health, once the death is a lot of patients to face
Fact。 However, in the face of such a disease, you do not worry, active and effective treatment is also very reliable. So, in the life of general
What causes the occurrence of uremia?
What causes uremia
Modern medicine thinks uremia is a series of complex syndrome which is caused by the disorder of internal biochemical process. Not a
An independent disease called renal failure syndrome or renal failure. The term PIORRY and HERITER described renal failure in 1840
Post proposed. Uremia is a result of almost all renal fibrosis, resulting in loss of renal function. Renal fibrosis is the early stage of renal injury
So, all kidney diseases should be paid attention to, timely standardized treatment, to prevent the occurrence of uremia critically ill.
Urea into the digestive tract in vivo accumulation of 1 digestive system in the intestines to form ammonia by bacterial urease, can stimulate the gastrointestinal mucosa caused by fiber
Induced inflammation, ulceration and bleeding even. A wide range of lesions, from the mouth, esophagus and rectum can be affected. In uremic esophagitis, gastritis and node
Enteritis is more common. Patients often have nausea, vomiting, abdominal pain, diarrhea, bloody stool and other symptoms.
2 heart, lung water retention of sodium, renal ischemia, increased renin secretion caused by long-term effects of hypertension in the heart can cause heart failure. Blood urine
In high into the pericardial and pleural can cause fibrinous pericarditis and cellulose pleurisy, pericardial and pleural friction sound can be heard during auscultation. Heart failure
Can cause pulmonary edema. Blood urea from the respiratory tract can cause inflammation of the respiratory tract, sometimes along the alveolar wall can be transparent membrane formation; pulmonary capillary permeability
In addition, there are a lot of fibrin and mononuclear cells in the alveolar cavity, and there are few neutrophils.
3 the hematopoietic system mainly changed into anemia and hemorrhage. Causes of anemia: when severe renal tissue damage erythropoietin deficiency. In vivo
Some of the metabolites, such as phenol and its derivatives, inhibit bone marrow hematopoietic function. Other toxins such as guanidine and its derivatives can shorten the survival of red blood cells
To accelerate the destruction of red blood cells and cause hemolysis. Excessive loss of transferrin from urine, resulting in the transport of iron in the body. Uremic patients often have
The bleeding tendency, manifested as gingival bleeding, epistaxis, hemorrhage of digestive tract. The causes of bleeding: toxic substances inhibit bone marrow, thrombocytopenia. 2
Some patients do not reduce the number of platelets, but bleeding tendency. This may be due to the blood of a class of toxic substances caused by platelet dysfunction
The role of platelet cohesion weaken and release of platelet factor third decrease.
4 in the skeletal system of urea often have low calcium. This may be due to: renal excretion of phosphate function decline, so the concentration of phosphate in the blood, calcium
Concentration decreased. In vivo accumulation of phosphate in the intestine and the intake of calcium into the synthesis of insoluble calcium phosphate, calcium absorption decreased, the increase in excretion. 1,
25- dihydroxycholecalciferol is vitamin D promote calcium absorption activity in the intestine, synthesized in the kidney. Chronic kidney disease, 1, 25- dihydroxy Cholecalciferol
Alcohol synthesis disorders, caused by intestinal calcium malabsorption, caused by hypocalcemia. When the lower the serum calcium can cause long-term uremic hyperparathyroidism, because
And generally cause bone decalcification, called renal osteodystrophy (renal osteodystrophy), the morphology and bone softening (osteomalacia) and capsule
Like (osteitis fibrosa cystica) osteitis fibrosa similar. The clinical use of 1 25- dihydroxycholecalciferol and similar drugs to treat these with kidney
The disease has a good effect on calcium metabolism disorders.
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