Why can not hormone treatment of nephrotic syndrome?
Why can not hormone cure nephrotic syndrome? Beijing Tong Shantang Chinese medicine hospital kidney disease experts said, want to understand the answer to this question, but also first know what is nephrotic syndrome. Nephrotic syndrome (nephrotic syndrome, NS), referred to as renal syndrome, refers to a variety of causes caused by glomerular basement membrane permeability with decreased glomerular filtration rate and other glomerular lesions Group of clinically similar syndromes, not independent of the disease. Typical manifestations of a large number of proteinuria, hypoproteinemia, high edema, hyperlipidemia. So why do not cure the hormone nephrotic syndrome?
First long-term use of glucocorticoid applications can cause water, salt, sugar, protein and fat metabolism disorders, the emergence of adrenal cortical hyperthyroidism. Manifested as centripetal obesity, resulting in calcium absorption disorders, resulting in osteoporosis, severe cases can also occur spontaneous fracture.
Followed by glucocorticoid can reduce the body's ability to prevent disease, is conducive to the growth and proliferation of bacteria and proliferation, induced or aggravated infection.
Then glucocorticoids promote protein breakdown, can delay granulation tissue formation, prevent trauma or surgical wound and other ulcer healing.
In addition, glucocorticoids have the role of anti-growth hormone, children's long-term application can inhibit bone growth and protein synthesis, affecting growth and development, pregnant women can also cause fetal malformations.
Finally, long-term use of glucocorticoid therapy, after the basic control of the symptoms, such as reductions too fast or sudden withdrawal, the original symptoms may appear rapidly or aggravated, known as the "rebound phenomenon." There are some symptoms of the original disease, such as myalgia, muscle rigidity, joint pain, said withdrawal symptoms (or withdrawal syndrome).
Through the above Beijing Tong Shantang Chinese medicine hospital kidney disease expert analysis, I believe we all understand the hormone can not cure nephrotic syndrome reasons. Hope that we know a lot about kidney disease knowledge, away from kidney disease.
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