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Why does chronic renal failure have anemia?

Gender:Female Age:53 2017-06-20 09:20
kidney: Chronic Renal Failure, Chronic Renal Failure, Chronic Renal Failure ,Anemia, Renal Failure
Illness: Why does chronic renal failure have anemia? I have a friend's mother has nephritis before, has been taking medicine, control is also good. But for a long time, there has been kidney failure. Recently for some time always nausea,  vomit, medication regardless, went to the hospital for treatment, doctors did routine blood test, turned out to be anemia.?
Sick time: unclear
Want to get help: Why does chronic renal failure have anemia?
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【1】

Anemia is the most common complication of chronic renal failure, but also can be part of the patient with anemia as the first symptom and treatment. No complications of chronic renal failure in anemia is positive pigment, positive cells, reticulocyte reduction, when combined with aluminum poisoning can show low pigment, small cell anemia. In patients with chronic renal failure to understand the causes of anemia, it is important to remember that in the treatment of chronic renal failure disease, must be symptomatic treatment for the cause, so as to faster recovery of good health.

【2】

Chronic renal failure patients the most common anemia is caused by reduced erythropoietin, erythropoietin mainly produced by glomerular cells, medullary stromal cells. Chronic renal failure, in addition to the kidneys produce erythropoietin site damage, the hemoglobin on the oxygen affinity decreased, the unit hemoglobin on the oxygen utilization increased, renal ischemia is relatively serious, resulting in erythropoietin main stimulus reduced Erythropoietin production was significantly reduced. There are toxins inhibit bone marrow, chronic renal failure when the accumulation of some of the toxic substances in the bone marrow has a direct inhibitory effect, leading to hematopoietic dysfunction.

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