diet for kidney disease
How does obesity affect the kidneys?

How does obesity affect the kidneys?

Obesity is associated with multiple kidney diseases, chronic glomerulonephritis, kidney stones, uremia renal transplantation prognosis, obesity patients are often associated with diabetes or hypertension, resulting in diabetic nephropathy and hypertensive...


Obesity is associated with multiple kidney diseases, chronic glomerulonephritis, kidney stones, uremia renal transplantation prognosis, obesity patients are often associated with diabetes or hypertension, resulting in diabetic nephropathy and hypertensive nephropathy. So how does  obesity affect the kidneys?

How does obesity affect the kidneys?

Obesity can directly increase the renal burden, increase glomerular filtration rate, renal blood flow and glomerular filtration fraction, change the glomerular hemodynamics, destroy the glomerular filtration barrier, and then lead to proteinuria.

Adipose tissue releases a variety of fat factors such as leptin adiponectin and resistin which promote cell proliferation extracellular matrix aggregation and renal fibrosis.

Obesity also activates RAAS (renin-angiotensin-aldosterone system), while RAAS activation and urine protein are also recognized as contributing factors to the progression of chronic kidney disease.

Obese patients are mostly accompanied by hyperlipidemia, hypertension, hyperglycemia, hyperuricemia and other symptoms.

So how should obese nephropathy patient prevent and cure? It is recommended that obese patients take RAAS blockers and weight loss to delay the progression of kidney disease. The protective effect on the kidney of obese patients is better than that of non-obese patients. RAAS blockers can significantly reduce the level of proteinuria in obese patients, but the effects of RAAS blockers decrease over time, so they cannot be used for long periods of time.

It is suggested that obese nephropathy patients should take healthy diet, reasonable exercise and scientific weight loss.

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